CYPs are mighty synthesis machines
CYPs are mighty synthesis machines This is an insightful article by a group at University of Dundee[…]
That will never be a drug!
“That will never be a drug!” How tempting it is to say that, because it’s almost always[…]
GIGO = garbage in, gold out?
GIGO = garbage in, gold out? In an effort by a team at AstraZeneca, novel PROTAC degraders[…]
Potent macrocycles, served as you like them…de novo
If there is one area that would benefit tremendously from de novo design tools, it is in[…]
Big things come in little packages
Big things come in little packages A recent article by a team in Genentech highlighted a RIPK1[…]
What does a mummy smell like? It’s all about the chemistry…
What does a mummy smell like? It’s all about the chemistry… I can honestly say that is[…]
Chemists love chiral molecules, until they don’t..
Chemists love chiral molecules, until they don’t… This paper by Peter O’Brien at University of York, and[…]
